Common variable immunodeficiency (CVID) and MxA-protein expression in blood leucocytes

Autoimmunity and infection in common variable immunodeficiency (CVID).

Common variable immunodeficiency (CVID) is a heterogeneous group of diseases, characterized by primary hypogammaglobulinemia. B and T cell abnormalities have been described in CVID. Typical clinical features of CVID are recurrent airway infections; lymphoproliferative, autoinflammatory, or neoplastic disorders; and autoimmune diseases among which autoimmune thrombocytopenia (ITP) is the most co...

Clinical and Immunological Spectrum of Common Variable Immunodeficiency (CVID).

We have analysed data from 150 patients initially classified as having CVID. About 10% had laboratory abnormalities suggesting known single gene disorders (eg: hyper-IgM syndrome), and in a few a genetic defect has been confirmed. We have attempted to sub-classify the remaining patients by analysis of their circulating lymphocytes. B lymphocyte markers have been used to estimate the numbers of ...

clinical and immunological spectrum of common variable immunodeficiency (cvid)

we have analysed data from 150 patients initially classified as having cvid. about 10% had laboratory abnormalities suggesting known single gene disorders (eg: hyper-igm syndrome), and in a few a genetic defect has been confirmed. we have attempted to sub-classify the remaining patients by analysis of their circulating lymphocytes. b lymphocyte markers have been used to estimate the numbers of ...

Co-existence of Common Variable Immunodeficiency (CVID) with Idiopathic Thrombocytopenic purpura (ITP)

Rapamycin reduces splenomegaly and lymphadenopathy in Common Variable Immunodeficiency ( CVID ) : A

A 54 year old female was hospitalised with anti-microbial-sensitive H. influenza pneumonia, her first major infection. Past medical history included prior motor vehicle accident, 160 pack year history of smoking and a recent diagnosis of chronic obstructive pulmonary disease (COPD). Medications on admission were Budesonide-Efomoterol, terbinafine and bupropion. There was no history of allergy, ...